ACTIVATION OF ARCUATE NUCLEUS GABA NEURONS PROMOTES LUTEINIZING HORMONE SECRETION AND REPRODUCTIVE DYSFUNCTION: IMPLICATIONS FOR POLYCYSTIC OVARY SYNDROMERESEARCH IN CONTEXT

Background: Enhanced GABA activity in the brain and a hyperactive hypothalamic-pituitary-gonadal axis are associated with polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility.Women with PCOS exhibit elevated cerebrospinal fluid GABA levels and preclinical models of Pushbutton PCOS exhibit increased GABAergic input to Gn

The article discusses interrogation tactics of a suspect involved in illegal fishing, hunting, or other aquatic resource exploitation, necessitating the formation of specific tactical recommendations regarding the conduct of interrogations of suspects in criminal proceedings of this category.Based on an analysis of pre-trial investigation practices

Structural glaciology yields important details about the evolution of glacier dynamics in response to climate change.The maps provided here document the occurrence and evolution of brittle and ductile structures on the tongue of Forni Glacier, Ortles-Cevedale Group, Central Italian Alps, between 2003 Spices and 2014.Through the remote sensing-based

Abstract Background Given that psychopharmacological approaches routinely used to treat mood-related problems may result in adverse outcomes in mood dysregulated adolescents at familial risk for bipolar disorder (BD), Mindfulness-Based Cognitive Therapy for Children (MBCT-C) provides an alternative effective and safe option.However, little is known